Transduction
Transduction Transduction is an event in which bacteriophages function as vectors/ vehicles to transfer of DNA from donor bacteria to recipient bacteria. Transfer of bacterial genes by phage was discovered by Zinder and Lederberg in 1952 in Salmonella typhimurium. Transduction mechanism is occur in two ways. 1. Generalized transduction 2. Specialized transduction The bacteriophage containing the bacterial DNA of donor is called transfusing phage. Bacteriophages are two types. i) Virulent phage: Virulent phage follow lytic cycle capable of causing bacterial infection and eventually destruction and death of bacterial cell e. g. T4 Phage ii) Temperate phage: Phage does not cause disruptic infection instead phage DNA incorporated into bacterial DNA and replicate Lysogenic and after sometime become virulent cause lysis. e. g. λ phage 1. Generalized transduction: In generalised transduction, a DNA fragment is transferred fr...